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HGG is a protein secreted by pituitary cells and is a peptide hormone that promotes human growth and regulates the metabolism of the body. hgh auxin mainly through the inhibition of muscle and adipose tissue utilization of glucose, while promoting liver gluconeogenesis and glycogen decomposition, so that blood sugar. HGg growth hormone can promote lipolysis, plasma free fatty acids increased. When hunger decreased insulin secretion, increased growth hormone secretion, so blood glucose utilization and increased fat use, when plasma glucose and free fatty acids increased.
Human growth hormone (hGH) is a protein secreted by adenohypophyseal cells and is a peptide hormone. Growth hormone produced by recombinant DNA technology referred to r-HGH. Normally, the growth hormone HGH is pulsatile and the secretion of growth hormone (hGH) is regulated by hypothalamic GHRH and somatostatin (GHIH) Affected by gender, age and circadian rhythm, secretion increased significantly during sleep. The main physiological function of growth hormone is to promote the growth of all other tissues except nerve tissue; promote the body’s synthesis and metabolism and protein synthesis; promote lipolysis; insulin antagonism; inhibition of glucose utilization and increased blood sugar and so on. Determination of serum growth hormone contributes to the diagnosis of ghrelin, acromegaly and hereditary growth hormone deficiency caused by growth hormone deficiency.
The growth hormone molecule consists of 191 amino acid residues with a relative molecular mass of 22,124 Daltons. Molecular structure with four α-helix so that growth hormone and its receptor can have a good combination. In terms of protein sequence, growth hormones and prolactin and chorionic prolactin are homologous evolved. Human growth hormones have a degree of specificity and, therefore, can only act on humans and primates, albeit highly similar to the growth hormones of other species.
There are several growth hormone is forms into the bloodstream, most of them with growth hormone-binding protein (GHBP) and another glycoprotein (GHBP) acid labile subunit, ALS) three together. A growth hormone binding protein is a protein that evolves from the growth hormone receptor.