Category: hormone

Quick Details about Testosterone Undecanoate

brand names Aveed, Andriol,etc.
Synonyms Aveed, Andriol, Undestor, Nebido, Pantestone, Restandol, Cernos Depot, Nebido-R, Reandron 1000
17β-[(1-Oxoundecyl)oxy]-androst-4-en-3-one
CAS Number 5949-44-0
Formula C30H48O3
Molar mass 456.70032 g/mol

Introductions about Testosterone Undecanoate

Testosterone undecanoate (USAN, BAN) (brand names Aveed, Andriol, Androxon, Cernos Depot, Nebido, Panteston, Restandol, Nebido-R, Reandron 1000, Undestor), or testosterone undecylate, is an androgen and anabolic steroid and a testosterone ester.It is used in androgen replacement therapy primarily for the treatment of male hypogonadism, and has also been investigated for use as a male contraceptive or as hormone replacement therapy in transgender men. Unlike other testosterone esters, testosterone undecanoate is available in both oral and intramuscular formulations. The Reandron 1000 formulation (Nebido in the United States) contains 1000 mg of testosterone undecanoate suspended in castor oil with benzyl benzoate for solubilisation and as a preservative, and is administered by intramuscular injection. As an excipient, benzyl benzoate has been reported as a cause of anaphylaxis in a case in Australia. Bayer includes this report in information for health professionals and recommends that physicians “should be aware of the potential for serious allergic reactions” to preparations of this type. In Australia, reports to ADRAC, which evaluates reports of adverse drug reactions for the Therapeutic Goods Administration, show several reports of allergic issues since the anaphylaxis case from 2011.
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. The elimination half-life and mean residence time of testosterone undecanoate are 2.5-fold and 4-fold longer than those of testosterone enanthate (the values for testosterone enanthate being 4.5 days and 8.5 days, respectively).

Uses of Testosterone Undecanoate

This medication is used in men who do not make enough of a natural substance called testosterone. Testosterone belongs to a class of drugs known as androgens. Testosterone helps the body to develop and maintain male sexual characteristics (masculinity), such as a deep voice and body hair. It also helps to maintain muscle and prevent bone loss, and is necessary for natural sexual ability/desire.

There are 8 steps for guiding injecting steroids successfully for you without any complications such as infections or simply very uncomfortable injections, and an unnecessarily sore injected area. Of course, the most important thing for you is to prepare the injection and stick it into the muscle tissue, than follows the instructions below step by step.

• Step 1: Choosing a Needle – There are numerous needle sizes at our disposal, and you need the right one to get the job done. There’s no reason to choose a massive needle, but you don’t want one that’s so small the oil will barely push through. In most all cases, a 23g-25g needle will serve your needs. As for the needle length, 1” is plenty long enough for most anyone, but 1.5” is also suitable. Some will find ½” needles to be sufficient, but only if they are injecting into a very low body-fat area. Regardless of the needle size you choose, you will always use a clean never before used needle each and every time.
• Step 2: Drawing Air – Before you draw your steroids into the syringe, the first step is to draw at a minimum the same amount of air into the syringe that matches the amount of oil you’ll be drawing into the syringe. This is not absolutely necessary, but it will make step four a lot easier. Further, most will find drawing a little more air than needed to be quite beneficial and make things even easier.
• Step 3: Empty the Air – Place the needle into the oil (the steroids you’re using) and push all the air in. This will allow you to draw the oil with ease; again, you don’t have to do this but there’s no point in skipping it.
• Step 4: Draw the Oil – Simply pull the plunger of the syringe back until the desired amount is obtained; most will find drawing in slightly more (a miniscule amount) to be useful. A side note; many choose to use a “Draw Needle” for this purpose; this refers to using a larger needle. In this instance, you will use a 20g-21g needle to draw your oil into the syringe as it is much easier and faster. If you choose this method, you will follow steps 2 and 3 with your draw needle, and then replace the needle with the needle you chose in step 1.
• Step 5: Remove Air Bubbles – Now that the oil is in the syringe, you will push the plunger forward while tapping your finger against the side of the syringe to remove all air bubbles. This will cause a little bit of oil to shoot out of the needle, but that’s why you drew up a little extra.
• Step 6: Disinfecting – Determine which muscle you’re going to inject and the specific location, and disinfect with alcohol. Putting alcohol on a cotton ball will work, but alcohol swabs are perfect for this purpose.
• Step 7: Plunge the Needle & Aspirate – Once the area is disinfected, plunge the needle into the desired location, but do not inject yet. Once the needle is firmly in place, pull the syringe back; this is what is known as Aspirating. When you aspirate, if blood fills into the syringe remove the needle and pick a new location. If blood has entered into the syringe, you have hit a vein or blood vessel, and if you inject there’s a chance you’ll fall prey to what is known as “Tren Cough.” Trenbolone is the most notorious anabolic steroid for causing this, but it can happen with even Testosterone. When you hit a vein or blood vessel, some of the steroid gets into the lungs, and causes a violent cough that can be quite frightening and painful. Your mouth will taste like metal, and some say their teeth even hurt, and you will cough more violently than you ever have before. Don’t let this scare you; if you aspirate and follow our recommendations you’ll be fine. If you aspirate and no blood enters the syringe, you’re ready to inject.
• Step 8: If you have followed steps 1-7 and no blood entered the syringe during step 7, you are ready to inject your steroid(s). Simply push the plunger until all the oil has entered the desired location.

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