Drostanolone Enanthate is strictly an underground anabolic androgenic steroid that is based on the discontinued Drostanolone Propionate compound known as Masteron. Masteron is a fairly old anabolic steroid first created in 1959 by Syntex and has been sold under several other brand names such as Masteril, Drolban and Metormon with Masteron remaining the most recognizable.
Test 600x During the 1970’s and 80’s Masteron enjoyed significant therapeutic success, particularly in the treatment of inoperable breast cancer. Despite its success in cancer treatment and other areas of medicine, in the late 1980’s and early 1990’s Masteron began to disappear from the U.S. and European markets and in modern times is no longer manufactured. Drostanolone is still an FDA approved anabolic steroid, but no U.S. pharmacy manufactures it.
During the 1970’s and heavily in the 1980’s Masteron become very popular among competitive bodybuilders. In fact, it has come to be viewed as an essential for contest prep for many bodybuilders and is a common favorite among recreational bodybuilders during their cutting cycles. Due to the Propionate ester that is attached Masteron must be injected at minimum three times per week with an every other day schedule being the most efficient. Because of the need for frequent injections and high demand for the steroid, many underground labs began manufacturing the Drostanolone hormone with the Enanthate ester attached. The new combination become very prominent in the early 2000’s and as such Masteron Enanthate was born. Masteron Enanthate is the same anabolic steroid as Masteron Propionate; the hormone itself has not been changed. The only difference in the two compounds is the attached ester, which affects the drug’s active life and release into the body.
Masteron Enanthate (Drostanolone Enanthate) is a dihydrotestosterone (DHT) based anabolic steroid. Drostanolone is simply the DHT hormone structurally altered. The alteration exists through the addition of a methyl group at carbon position 2. This ensures the hormone doesn’t suffer metabolic breakdown brought on by the 3-hydroxysteroid dehydrogenase enzyme found in the skeletal muscle. This simple structural change also makes the hormone far more anabolic, and that gives us Drostanolone. Once the hormone has been created, altered from DHT, an ester is then attached, and in this case the ester attached is Enanthate. Enanthate is not a steroid or a drug but nothing more than a timing tool used for a drug.
As with Masteron Propionate, Masteron Enanthate is well known for being one of the only anabolic steroids that carries strong anti-estrogenic properties. This anabolic steroid cannot increase estrogen levels; in fact, it can actually decrease estrogen levels in the body. It is for this reason Drostanolone was successful in breast cancer treatment with the combination of Drostanolone and Tamoxifen being very commonplace for many years. Bodybuilders welcome this trait due to estrogen often being difficult to control with many steroids and lower estrogen levels often leading to a harder and more defined look during the cutting phase.
Masteron Enanthate possesses some of the most misleading anabolic and androgenic ratings of any anabolic steroid, although not nearly as misleading as Halotestin and Anavar. Drostanolone has a binding affinity to the androgen receptor that is five times greater than testosterone, which not only produces a harder look it can also have a positive impact on fat loss. All anabolic steroids can help improve the metabolic rate, but those with a strong androgen binding affinity can have an impact on direct lipolysis.