Clomiphene Citrate is a powerfully effective anti-estrogen officially classified as a Selective Estrogen Receptor Modulator (SERM). In many ways, it is very similar to another popular SERM in Nolvadex (Tamoxifen Citrate). Clomid first gained worldwide attention in the early 1970’s as a strong fertility aid and is still used for that purpose today. It is also one of the most commonly used SERM’s by anabolic steroid users. No, it is not an anabolic steroid but can be used to combat estrogenic side effects sometimes caused by anabolic steroids. It can also be used as a Post Cycle Therapy (PCT) medication in order to stimulate suppressed testosterone production due to anabolic steroid use. PCT use of Clomid is the most common purpose and most beneficial point of use for the anabolic steroid user.
Clomiphene Citrate is a SERM that is specifically used as a fertility aid due to its ability to enhance the release of gonadotropins. Clomid has the ability to oppose the negative feedback of estrogens on the Hypothalamic-Pituitary-Ovarian-Axis. This will increase the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) significantly. By increasing gonadotropin release, this can lead to the egg being released, thereby increasing the chance of conception.
Clomid also carries strong anti-estrogen properties that could be used therapeutically, but its anti-estrogen properties are most commonly associated with anabolic steroid use. Testosterone and many testosterone derived steroids have the ability to convert to estrogen through testosterone’s interaction with the aromatase enzyme. As estrogen levels rise, this can lead to gynecomastia and excess water retention. Heavy water retention can also promote high blood pressure. By supplementing with Clomid during anabolic steroid use, the SERM will bind to the estrogen receptors, therefore inhibiting the estrogen hormone from binding. This can be very useful in combating gynecomastia, as when Clomid binds to the receptor it prevents estrogen from stimulating the mammary tissue. It can also have a positive impact on water retention, but as it won’t actively reduce serum estrogen levels it’s sometimes not enough.
Clomid also possess functioning traits that are beneficial to the anabolic steroid user post anabolic steroid use. Specifically we’re referring to Post Cycle Therapy (PCT). In men, Clomid also has the ability to stimulate the pituitary to release more LH and FSH, which will in turn stimulate enhanced natural testosterone production. This is extremely beneficial to the anabolic steroid user post cycle as natural testosterone levels will be very low due to suppression caused by anabolic steroid use.